Two electrode voltage clamp electrophysiology (TEVC) is a commonly used electrophysiology method for oocyte recording, and npi electonic’s TEC is the best known amplifier for this purpose because of its precise measurement of ionic current flow across cell membranes. In this video, Dr. Dempski from Worcester Polytechnic Institute shows a powerful method to study the conformational changes of membrane proteins in situ by simultaneously monitoring fluorescence and current changes using voltage-clamp fluorometry with npi’s TEC amplifier. This method also allows investigators to manipulate intracellular and extracellular environments including ion composition, pH, and ligands to study membrane protein dynamics.

 [Click here for video]

We are a Long Island based scientific instrumentation company seeking a motivated applications specialist. The ideal candidate will have a knack for technology which they will use to sell and support our products in a niche research environment geared towards life scientists using electrophysiology and/or imaging techniques.

Job Responsibilities

Consistently position and promote ALA brand and our distributed products through customer visits, promotional events and materials

Actively visit customers throughout the entire North American region to provide technical sales and support for our different product lines

Insure successful adoption of our products to customer’s satisfaction

Attend and help organize relevant scientific meetings and conferences

Become completely proficient in the use of our equipment including hardware and software

Provide superior technical support via telephone, email, and site visits

Provide technical training and set-up to customers as needed

Qualifications:

The ideal candidate should have a BS/MS degree (preferred) in a hard science; preferably biology, physiology, neuroscience, or biomedical engineering; can be working towards graduate degree

The position requires travel throughout North America 8 to 12 times per month including travel time.   A valid driver’s license is needed. Will consider a foreign national who is legal to work in the US.

Other qualifications:

Excellent English communication skills including oral and written

Life Science Lab Experience is preferred

Self-Starter

Detail oriented

Personable

Good with technology

Electrophysiology experience is a big plus

Job includes full benefits package: (Medical/Dental, Retirement Plan, Vacation/Sick days).

Competitive salary that is commensurate with experience.

Epidural cortical signals were detected with npi electronic’s differential amplifier EXT 10-2F to study the relationships between the calcium signals and the electrical activity. This configuration made it possible to record global ‘up states’ of the epidural potentials, although not the local electrical responses near the fiber.

[Click here for abstract]

npi electronic’s EXT-02F is widely used for in vivo recording of C-fiber-evoked field potentials through stimulation of the sciatic nerve using npi’s ISO-STIM 01D. Results show the functional role of dura mast cells in nociception and synaptic plasticity in the superficial spinal dorsal horn.

[Click here for abstract]

Congratulations to James Demas (St. Olaf College) for being the winner of the 32" Toshiba LCD TV Scientist Challenge prize!

We appreciate all who replied to our Wireless Recording System challenge question and entered to win. 

Question: What is the maximum sampling rate you can use, and at what resolution?

Answer: The maximum sampling rate is 20kHz simultaneously on 4 or 8 channels at a 16 bit resolution.

[Click here for abstract]

[Click here for abstract]

[Click here for abstract]