8-channel Valve Control System

Perfusion is critical in most biological applications, both for maintaining the viability of preparations and establishing experimental conditions. Electronic control of solution exchange improves fluid delivery and enhances reproducibility over manual methods. With the BPS-8 systems, you can configure systems for the basic requirements of the student lab or you can optimize them for the most demanding applications of patch-clamp recording and / or imaging.

* New redesigned Lee Co. mini valve exclusively for ALA.

8-channel Valve Control System

Perfusion is critical in most biological applications, both for maintaining the viability of preparations and establishing experimental conditions. Electronic control of solution exchange improves fluid delivery and enhances reproducibility over manual methods. With the BPS-8 systems, you can configure systems for the basic requirements of the student lab or you can optimize them for the most demanding applications of patch-clamp recording and / or imaging.

The BPS-8 are modular systems that allow for fast and easy setup. All systems are designed to minimize electronic noise, therefore it is suited for electrophyiological recordings. You can control your valve openings from the BPS-8C valve controller, manually, or from your data acquisition software using the convenient TTL inputs on the controller housing. Gravity-driven systems are affordable and easily adjusted by positioning the reservoir manifold; more expensive pressure driven systems make precise adjustment of flow rates even easier.

ALA has two valve options: three-way pinch valves or soleniod valves made exclusively for ALA by the Lee Co. The pinch valves allow selection of default-open or default-closed positions to reduce heat dissipation to solutions. The pinch tubing is cleaned by rinsing the tubing; because there are no internally wettable surfaces, maintenance consists of periodically exchanging pinch tubing. ALA's solenoid valves are optimized for high-speed solution exchange. These valves feature a biologically inert internally wettable surface and give valve opening times of less than two msec. All ALA systems can be configured with 5, 10 or 60 ml reservoirs. As with all ALA instruments, custom configurations are also available.

All gravity systems consist of a magnetic stand that hold the valve and the reservoir manifolds, an electronic valve controller, tubing, and a standard Minimanifold™ outlet. The standard reservoirs are 60ml luer lock syringes and include 3 way stop cock luer valves. The entire reservoir assembly as well as individual reservoirs can be moved up/down in order to balance fluid flow. The fluid is directed into the standard 4 to 1 inlet (MMF-8, Minimanifold™) and then flows out a single output tube. Options include different reservoirs sizes and other 4 to 1 perfusion outlets (MLF-8, Millimanifold™).

All pressure systems (BPS-8SP shown) consist of a magnetic stand that hold the valve and pressure reservoirs manifolds, an electronic controller, and tubing. Each pressurized system comes standard with the Minimanifold™outlet in case the user wants to switch to gravity for a particular study. Other outlets can be via an optional Millimanifold™ for large area focal perfusion. For the ultimate in fast focal drug application the system can be used with ALA’s Micromanifold® (QMM-8 ). Pinch or soleniod valves are availabvle. To pressurize the system, the optional PR-10, Pressure Regulator is suggested.

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All BPS systems can be configured with the following options: