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Multi-Electrode Recording System for In-vivo & In-vitro

ME Systems are complete systems for data acquisition from standard multielectrode arrays, perfect for in vivo and in vitro applications. Raw data from electrodes can be amplified by either a filter amplifier with fixed gain (FA) or an amplifier with programmable gain (PGA), and then acquired by the MC_Card of the connected computer. In case of a PGA, the gain can be flexibly adjusted with the program FiltAmp. The amplifier has to be ordered separately. Recorded data is graphed, analyzed, reviewed, and exported with powerful yet easy-to-use MC_Rack program. Systems with 16, 32, 64, and 128 input channels are available under the name ME16System, ME32System, and so on.

Multi-Electrode Recording System for In-vivo & In-vitro

ME Systems are complete systems for data acquisition from standard multielectrode arrays, perfect for in vivo and in vitro applications. Raw data from electrodes can be amplified by either a filter amplifier with fixed gain (FA) or an amplifier with programmable gain (PGA), and then acquired by the MC_Card of the connected computer. In case of a PGA, the gain can be flexibly adjusted with the program FiltAmp. The amplifier has to be ordered separately. Recorded data is graphed, analyzed, reviewed, and exported with powerful yet easy-to-use MC_Rack program. Systems with 16, 32, 64, and 128 input channels are available under the name ME16System, ME32System, and so on.

Hardware
Complete plug and play recording system for in vivo and in vitro applications including:

 

Data acquisition

Recording from up to 128 channels is easy with the MC_Card hardware and the MC_Rack software. The MC_Card is an A/D board that converts analog signals in real time into digital data streams at sampling rates of up to 50 kHz. You will not miss even the fastest signals. You configure the input voltage range from +/- 400 mV to +/- 4V in the MC_Rack program.


Software

Combined with the MC_Card hardware, MC_Rack forms a complete system for reliable acquisition and analysis of electrophysiological data. Recording, graphing, and analyzing in real time extracellular activities of excitable cells, for in vitro and in vivo preparations - all achieved with one powerful yet easy-to-use solution. Features include a virtual oscilloscope, a filter, an event detector, a spike sorter, automatic feedback, sound, and various analysis tools. You set up a virtual instrument rack, which is convenient and saves space on your workbench.


Virtual Rack

The main power of MC_Rack is its great flexibility. You can combine various virtual instruments according to your experimental setup. It is up to you, which data streams are displayed on the screen, which are saved, which are analyzed, and so on.

Operating system: Windows 98, ME, NT, 2000, or XP; English and German versions supported.


Data Analysis

Various parameters can be extracted in online or offline analysis from the data streams of your choice. Results are graphed, saved, and can be exported to other programs for further analysis. For example, you can easily analyze spike rates, field potential amplitudes, areas, minima, and maxima. You choose between several graph types, for example overlay, raster, or false color plots. You can also average sweeps to reduce the noise level and to enhance your signals, for example, to detect field potentials or for evoked potential analysis. Noise usually stems from arbitrary signals, where "real" signals should follow a pattern, that is, the signal event is linked to a stimulus or a trigger signal. Therefore, averaged noise signals cancel each other out and response signals become visible.


System Configurations

MCS provides complete solutions for stimulation, recording, data amplification and acquisition, and analysis, that are perfect for in vivo and in vitro applications.
The ME Setups PDF gives you an overview over the various systems and possible combinations of 64 channel systems with 8 miniature preamplifiers. Other setups with a different number of channels are set up likewise. These setups are to be understood as suggestions; you can define your custom setup as well. Please refer to the separate product descriptions on this web site to obtain more information. Complete setups for in vivo stimulation and recording can be combined with any standard microelectrode array such as the Michigan Probe. MCS products are easily adaptable to your experimental requirements. You can use your custom laboratory equipment in combination with any MCS product. Do not hesitate to contact MCS or your local retailer if you are interested in a particular setup or adaptor.

ME system setups pdf-file 3,0 MB

for technical specifications on the ME system components view the pdf files below:

 

Hardware datasheet : Mc_Card

Amplifiers datasheet : FA | MEA1060-1 | MEA1060-2 | MPA | PGA

array datasheet : FlexMEA

All downloads are in pdf format. Use Acrobat Reader to view. If you do not have the latest Reader, download it from the Adobe webpage for free

To save a pdf file to your local machine, right mouse click on link and choose "Save Target As...". You then choose the destination folder you want to save the pdf file to.

 


ME system : manual

Mc_Rack : manual

Configuration guide : ME system setups pdf-file 3,0 MB


 

Accessories for In Vivo systems
MCS BB-16BNC 16 channel BNC breakout box
MCS BB-32BNC 32 channel BNC breakout box
MCS BB-64BNC 64 channel BNC breakout box
MCS SB8x8 MPA DB9 outputs to 68 pin SCSI output - for up to 8 MPA amps
MCS SB8x8BC MPA DB9 outputs to 68 pin SCSI output - for up to 8 MPA amps. Includes Blanking Circuit
MCS PS20W Power supply for MPA, PA, FA, and PGA amplifiers
MCS 65OFFBOX 64 channel switch box w SCSI input and output
Programmable Gain Amplifiers
MCS PGA-16 16 channel programmable gain amplifier
MCS PGA-32 32 channel programmable gain amplifier
MCS PGA-64 64 channel programmable gain amplifier
MCS PGA-1632 16 Input, 32 Out Channel programmable gain amplifier
MCS PGA-3264 32 Input, 64 Out Channel programmable gain amplifier
In-Vivo MPA Miniature Preamplifier (headstage type)
MCS MPA-8 No filter, DC coupled headstage preamp, w/gain=10, 8 channels
MCS MPA-16 No filter, DC coupled headstage preamp, w/gain=10, 16 channels
MCS MPA-32 No filter, DC coupled headstage preamp, w/gain=10, 32 channels
MCS MPA-48 No filter, DC coupled headstage preamp, w/gain=10, 48 channels
MCS MPA-64 No filter, DC coupled headstage preamp, w/gain=10, 64 channels
8-Trode electrodes use w/ MPA headstages and other amplifiers
Acute style with connector attached to shaft
ALA 8T-AC-XXX Acute style 8-trode, random tip, buzzed out pads
ALA 8T-AC-XXX-DP Acute style defined pattern tip: specify spacing, pattern, angle
ALA 8T-AC-XXX-DPC Acute style defined pattern, custom (various specs, please consult ALA)
Chronic Style w/ short shaft for skull mounting w/ tether to connector
ALA 8T-CR-XXX-TT Basic chronic 8-trode, random tip, buzzed out pads
ALA 8T-CR-XXX-TT-DP Defined pattern tip: Specify spacing, pattern, angle
ALA 8T-CR-XXX-TT-DPC Defined pattern, custom (various specs, please consult ALA)
Defined Pattern: 4 pads in a row on one side, four pads in opposite row (180 degrees) or all pads on one side in a row. Specific distance between pads, defined custom patterns must be discussed with ALA. Basic connector is Omnetics Nanoconnector, other connectors can be supplied by the customer with approval. (No discount for customer supplied connector.) XXX= shaft length, TT = tether length
MCS 8T-MPA-CON 8-Trode to MPA headstage adaptor - small PCB b/w both
ALA 8T-LMP-AMP-XX Specific amplifier jumper to 8-TRODE connector xx=distance b/w jumper/conn.

 

Ordering Information
MCS ME-128-Sys 128 channel high speed data acquisition system
MCS ME-64-Sys 64 channel high speed data acquisition system
MCS ME-32-Sys 32 channel high speed data acquisition system
MCS ME-16-Sys 16 channel high speed data acquisition system
MCS MEA-FLEX Flexible Multi-Electrode Array (x4)