The function of neuronal circuits and systems can only be studied with preparations and experimental models where neurons are connected together to form neural networks. In vitro preparations such as acute brain slices and organotypic slices are ideal models from which to investigate neural circuits. Acute slice and organotypic preparations are used in conjuction with multielectrode arrays to record from many neurons, or populations of neurons, simultaneously. Experimenters can utilise these systems for diverse projects including, long term potentiation in hippocampal slices, micro electroretinograms from retinal explants or spontaneous rhythmic activity from cardiomyocyte cultures.

Equipment:

• MCS ME system